Brands / DefenAge / DefenAge Clinical Power Trio
  • DefenAge Clinical Power Trio
  • DefenAge Clinical Power Trio box shows anti-aging set with BioSerum, Barrier Balance Cream and 2 Minute Reveal Masque kit go
  • DefenAge Clinical Power Trio set shows BioSerum, Barrier Balance Cream and Reveal Masque with Age-Repair Defensins benefits.
  • DefenAge Clinical Power Trio Plus box and products show skin renewal system for fine lines, hydration and resurfacing cream.
  • DefenAge- Clinical Power Trio-The Skin Spot
  • DefenAge Clinical Power Trio
  • DefenAge Clinical Power Trio box shows anti-aging set with BioSerum, Barrier Balance Cream and 2 Minute Reveal Masque kit go
  • DefenAge Clinical Power Trio set shows BioSerum, Barrier Balance Cream and Reveal Masque with Age-Repair Defensins benefits.
  • DefenAge Clinical Power Trio Plus box and products show skin renewal system for fine lines, hydration and resurfacing cream.
  • DefenAge- Clinical Power Trio-The Skin Spot

DefenAge Clinical Power Trio

DefenAge Clinical Power Trio is a three-step anti-aging skincare regimen combining 8-in-1 BioSerum, 24/7 Barrier Balance Cream, and 2-Minute Reveal Masque to improve the visible appearance of fine lines, wrinkles, pigmentation, pores, texture, and hydration.

Regular price $365.00
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Product Perks

  • Firms and reduces fine lines
  • Clarifying & brightening
  • Hydrates dry skin
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  • PRODUCT DESCRIPTION

  • HOW TO USE

  • INGREDIENTS

  • SHIPPING & RETURNS

  • FAQ'S

Product Description

DefenAge Clinical Power Trio is a complete 3-step anti-aging skincare system designed to address 16 signs of aging, with initial results appearing in as little as one week. This clinical power trio combines the 8-in-1 BioSerum, 24/7 Barrier Balance Cream, and 2-Minute Reveal Masque — all powered by DefenAge's exclusive Age-Repair Defensins® technology.

The 8-in-1 BioSerum smooths, firms, brightens, and rejuvenates skin as the final step of your routine. The 24/7 Barrier Balance Cream hydrates and strengthens the skin barrier for lasting protection. The 2-Minute Reveal Masque exfoliates with Triple Enzyme Technology and ultra-fine sugar crystals, refining pores and smoothing texture in just two minutes. Together, this defenage skincare system offers a complete solution for anyone looking for the best skincare system to address multiple signs of aging at once. 

For additional products targeting aging skin and wrinkles, explore The Skin Spot's Anti-Aging Skin Care Products collection.

Product Size:

  • 3-piece set
  • 8-in-1 BioSerum 1 fl oz (30 ml)
  • 24/7 Barrier Balance Cream 1.5 fl oz (45 ml)
  • 2-Minute Reveal Masque 2.5 oz (71 g)

Benefits of Clinical Power Trio

  • Complete 3-step system addressing 16 signs of aging
  • Initial results appear in as little as one week
  • Powered by Age-Repair Defensins® technology in all three products
  • Hydrates, smooths, brightens, and evens skin tone
  • Exfoliates and minimizes the appearance of pores
  • Decreases the appearance of fine lines and wrinkles
  • Includes full-size 8-in-1 BioSerum, 24/7 Barrier Balance Cream, and 2-Minute Reveal Masque

Skin Types

  • Mature
  • Normal
  • Oily
  • Dry
  • Combination

Related Skin Concerns

  • Damaged Skin
  • Dull Skin
  • Uneven Skin Tone
  • Aging Skin
  • Dry Skin

Applicable Body Parts

  • Face
  • Neck

How To Use

Proper Clinical Power Trio Usage

Step 1: 24/7 Barrier Balance Cream

Use morning and evening after cleansing. Apply up to two pumps to fingertips and gently massage over the entire face while skin is still moist. Avoid the eye area. Wait approximately 30 seconds before applying the BioSerum.

Step 2: 8-in-1 BioSerum

Apply after the Barrier Balance Cream. Use one pump around the eyes and over the face. Apply a second pump to the neck and décolleté. Follow with sunscreen during your morning routine.

Step 3: 2-Minute Reveal Masque

Use once or twice weekly after cleansing. Thoroughly dry the skin, then apply approximately a quarter-sized amount to the face and jawline. Gently massage with dry fingertips in circular motions for 20 seconds or less depending on skin sensitivity. Leave on for two minutes. Add water to your fingertips and massage until the crystals dissolve, then rinse thoroughly. Follow with the 24/7 Barrier Balance Cream.

Ingredients

Key Ingredients

  • Age-Repair Defensins®
    • These defensins mimic the body's natural ability to signal cells to create new skin via bio-synthesis.
  • Niacinamide
    • Strengthens the skin barrier and smooths texture while reducing inflammation and redness.
  • Hyaluronic Acid
    • Provides intense hydration and minimizes the appearance of fine lines and wrinkles.
  • Sea Whip
    • Contains properties to combat irritants and swelling while hydrating and soothing skin.
  • Triple Enzyme Technology
    • Papaya, pumpkin, and pomegranate enzymes gently exfoliate for smoother and brighter skin.
  • Ultra-Fine Sugar Crystals
    • Smooth the skin by exfoliating the surface and revealing a rejuvenated, more even complexion.
  • Rosemary Leaf Extract
    • Soothes the skin and decreases inflammation and redness.

All Ingredients

  • 24/7 Barrier Balance Cream: Water (Aqua), Carthamus Tinctorius (Safflower) Oleosomes, Butyrospermum Parkii (Shea) Butter, Macadamia Integrifolia Seed Oil, Niacinamide, Yeast Extract, Ammonium Acryloyldimethyltaurate/ VP Copolymer, Helianthus Annuus (Sunflower) Seed Oil, Phospholipids, Alpha-Defensin 5, Beta-Defensin 3, Hyaluronic Acid, Ophiopogon Japonicus Root Extract, Hydrolyzed Candida Saitoana Extract, Sea Whip Extract, Lycium Chinense Fruit Extract, Vaccinium Angustifolium Fruit Extract, Vaccinium Macrocarpon Fruit (Cranberry) Fruit Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Panthenol, Albumin, Tocopheryl Acetate, Ubiquinone, L-Alanyl-L-Glutamine, Leuconostoc/Radish Root Ferment Filtrate, Xanthan Gum, Phytic Acid, Polysorbate 20, Caprylic/Capric Triglyceride, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Potassium Sorbate, Sodium Chloride.
  • 8-in-1 BioSerum: Water (Aqua), Cyclopentasiloxane, Glycerin, Niacinamide, Sinorhizobium Meliloti Ferment Filtrate, Dimethicone, Polysorbate 20, Dimethicone/Vinyl Dimethicone Crosspolymer, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Ammonium Acryloyldimethyltaurate/VP Copolymer, Phospholipids, Alpha-Defensin 5, Beta-Defensin 3, Palmitoyl Tripeptide-38, Sodium Hyaluronate, Arabidopsis Thaliana Extract, Sea Whip Extract, Ergothioneine, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Offinalis (Rosemary) Leaf Extract, Tocopheryl Acetate, Ubiquinone, Leuconostoc/Radish Root Ferment Filtrate, Albumin, L-Alanyl-L-Glutamine, Caprylic/Capric Triglyceride, Cetyl Hydroxyethylcellulose, Lecithin, Hydroxypropyl Cyclodextrin, Phytic Acid, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Sodium Chloride.
  • 2-Minute Reveal Masque: Butylene Glycol, PEG-8, Tapioca Starch, Sucrose, Titanium Dioxide, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Polysorbate 60, Carica Papaya (Papaya) Fruit, Papain, Aloe Barbadensis Leaf Juice, Lactobacillus/Pumpkin Ferment Extract, Lactobacillus/Punica Granatum Fruit Ferment Extract, Sea Whip Extract, Cananga Odorata Flower Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Caprylic/Capric Triglyceride, Lactic Acid, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol.

Shipping & Returns

Items will typically ship within 2-10 days of placing your order under the standard shipping option. For our return policy, please click here.

FAQs

Clinical Power Trio FAQs

What is the DefenAge Clinical Power Trio?

The DefenAge Clinical Power Trio is the brand's core three-step skincare regimen. It combines the 8-in-1 BioSerum, 24/7 Barrier Balance Cream, and 2-Minute Reveal Masque to address multiple visible signs of skin aging.

What does the DefenAge Clinical Power Trio help with?

The regimen is designed to improve the visible appearance of fine lines, wrinkles, pigmentation, pore size, skin texture, hydration, and overall skin quality. These areas were among the measures evaluated in the clinical study of the Trio.

How often should I use the DefenAge Clinical Power Trio?

The 24/7 Barrier Balance Cream and 8-in-1 BioSerum are used twice daily, morning and evening. The 2-Minute Reveal Masque is used once or twice weekly.

How long does DefenAge Clinical Power Trio take to work?

DefenAge states that initial visible results can appear during the first week, while the full range of visible results develops with consistent use over approximately six weeks.

Does the DefenAge Clinical Power Trio have clinical studies?

Yes. The Clinical Power Trio was evaluated in a multi-center, placebo-controlled clinical study published in the Journal of Drugs in Dermatology. DefenAge also states that its Age-Repair Defensins technology is supported by more than 30 clinical and consumer studies.

Can I use the Clinical Power Trio as my complete skincare routine?

Yes. DefenAge positions the Clinical Power Trio as its core three-step regimen and states that it can be used as a standalone routine or layered with products such as vitamin C, retinol, or sunscreen.

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