Product Description
DefenAge 8-in-1 BioSerum is a professional-grade anti-aging serum formulated with Age-Repair Defensins to address multiple visible signs of skin aging. This lightweight facial serum helps improve the appearance of fine lines, wrinkles, uneven tone, dullness, and loss of firmness while supporting smoother, brighter, more youthful-looking skin. Its multi-benefit formula makes it a versatile addition to an age-defying skincare routine for those seeking targeted skin renewal without a heavy feel.
Designed to complement a complete DefenAge skincare regimen, this 8-in-1 BioSerum delivers concentrated care for aging and stressed skin. Use it consistently to help enhance skin texture, radiance, firmness, and overall appearance. It pairs well with daily moisturization and other targeted treatments, making it an effective option for anyone looking for an anti-aging face serum that addresses multiple concerns in one step.
Clinical Studies
In a 12-week clinical study of the DefenAge Clinical Power Trio, which includes 8-in-1 BioSerum, participants showed improvements in the appearance of fine lines, wrinkles, pigmentation, skin texture, hydration and overall skin quality.
Product Size: 1.5 fl oz (45 ml)
Benefits of 8 in 1 BioSerum
- 8-in-1 multi-corrective serum powered by Age-Repair Defensins® technology
- Diminishes the appearance of fine lines and wrinkles
- Improves the appearance of firmness and facial contour while smoothing visible texture.
- Brightens and evens skin tone, targeting hyperpigmentation
- Improves the appearance of redness and supports a calmer-looking complexion.
- Supports skin-barrier function and improves the appearance of firmness and elasticity.
- Lightweight application, layered as the final step in your routine
- Suitable for the face, neck, and décolleté
Skin Types
- Mature
- Normal
- Oily
- Dry
Related Skin Concerns
- Dry Skin
- Dull Skin
- Uneven Skin Tone
- Aging Skin
Applicable Body Parts
- Face
- Neck
- Décolleté
How To Use
Proper 8-in-1 BioSerum Usage
- Apply one pump of BioSerum to your fingertips.
- Gently spread the serum over the face, beginning around the eye area.
- Massage evenly across the entire face.
- Apply one additional pump to the neck and décolleté.
- Use the BioSerum as the final skincare step.
Ingredients
Key Ingredients
Age-Repair Defensins®
Alpha-Defensin 5 and Beta-Defensin 3 are defensin molecules used in DefenAge's proprietary Age-Repair Defensin technology. DefenAge describes these molecules as signaling components involved in the skin's natural renewal processes.
Niacinamide
Niacinamide, a form of vitamin B3, supports epidermal barrier function and moisture retention while improving the appearance of uneven tone, dullness and redness.
Hyaluronic Acid
Sodium hyaluronate, a form of hyaluronic acid, binds water within the skin and supports hydration, helping improve the appearance of fine lines and surface texture.
Palmitoyl Tripeptide-38
Palmitoyl Tripeptide-38 is a signal peptide used in anti-aging skincare formulations to support the appearance of smoother, firmer skin and reduce the visible appearance of wrinkles.
Sea Whip
Sea Whip Extract is a marine botanical ingredient used to condition and soothe the appearance of skin while supporting a comfortable skin feel. DefenAge also identifies Sea Whip as one component of the BioSerum's multifunctional formulation.
Antioxidant Blend
The formula includes antioxidants such as ergothioneine, tocopherol-related vitamin E ingredients, ubiquinone and botanical extracts, helping support skin against environmental stressors.
All Ingredients
Water (Aqua), Cyclopentasiloxane, Glycerin, Niacinamide, Sinorhizobium MelilotiFerment Filtrate, Dimethicone, Polysorbate 20, Dimethicone/Vinyl Dimethicone Crosspolymer, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Ammonium Acryloyldimethyltaurate/VP Copolymer, Phospholipids, Alpha-Defensin 5, Beta-Defensin 3, Palmitoyl Tripeptide-38, Sodium Hyaluronate, Arabidopsis Thaliana Extract, Sea Whip Extract, Ergothioneine, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, SH Oligopeptide-1, Tocopheryl Acetate, Ubiquinone, Leuconostoc/Radish Root Ferment Filtrate, Albumin, L-Alanyl-L-Glutamine, Caprylic/Capric Triglyceride, Cetyl Hydroxyethylcellulose, Lecithin, Hydroxypropyl Cyclodextrin, Phytic Acid, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Sodium Chloride.
Shipping & Returns
Items will typically ship within 2-10 days of placing your order under the standard shipping option. For our return policy, please click here.
FAQs
8 in 1 BioSerum FAQs
What is DefenAge 8-in-1 BioSerum?
DefenAge 8-in-1 BioSerum is a multifunctional anti-aging serum designed to address several visible signs of aging, including fine lines, wrinkles, uneven tone, pigmentation, dullness, firmness and hydration. Its signature technology is the Age-Repair Defensin Complex.
Is DefenAge 8-in-1 BioSerum a retinol serum?
No. DefenAge states that the 8-in-1 BioSerum does not contain retinol. Instead, the brand positions its Age-Repair Defensins as an alternative approach to retinol-based anti-aging skincare.
Can I use DefenAge 8-in-1 BioSerum on my neck?
Yes. DefenAge's usage instructions recommend one pump for the face and another pump distributed over the neck and décolleté.
Is DefenAge 8-in-1 BioSerum good for acne-prone skin?
DefenAge states that the BioSerum is suitable for acne-prone skin when used as directed and recommends not exceeding the recommended amount.
What are the main ingredients in DefenAge 8-in-1 BioSerum?
Key ingredients include Age-Repair Defensins, niacinamide, sodium hyaluronate, Palmitoyl Tripeptide-38, Sea Whip extract and antioxidant ingredients.
How long does DefenAge 8-in-1 BioSerum take to work?
DefenAge describes the product as providing some immediate improvements in smoothness and radiance, while longer-term visible rejuvenation develops with consistent use. The brand has also published clinical and product materials discussing results over several weeks.
Why is the 8-in-1 BioSerum layered last in a skincare routine?
DefenAge recommends applying 8-in-1 BioSerum as the final skincare step because it contains the brand's highest concentration of Age-Repair Defensins. Applying your other treatment products first allows them to be used before the BioSerum. In the morning, apply sunscreen after the BioSerum.