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SkinCeuticals P-TIOX Anti-Wrinkle Peptide Serum

SkinCeuticals P-TIOX Anti-Wrinkle Peptide Serum

A peptide-powered anti-wrinkle serum that smooths expression lines, boosts radiance, and delivers glass-like skin without needles.

Core Benefits

  • Visibly reduces 9 different types of expression lines, including some areas that traditional neurotoxin injections may not reach.
  • Reveals “glass-skin” radiance in just one week of consistent use.
  • Provides intense 24-hour hydration to help maintain smooth, supple skin.
  • Physician-tested formula that can complement neurotoxin injections or be used alone for advanced wrinkle correction without needles.
  • Suitable for all skin types and tones, even sensitive skin.
  • Free from fragrance, silicone, and parabens for a gentler application.

Size

30 mL / 1 fl oz
$150
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SkinCeuticals P-TIOX is an anti-wrinkle peptide serum designed to visibly reduce expression lines, fine lines, forehead wrinkles, crow’s feet, smile lines, and neck lines while revealing glass skin radiance. Inspired by neurotoxin injections, this wrinkle-modulating serum combines an advanced peptide complex with 5% polyhydroxy acid, 5% niacinamide, and 1% laminaria extract to improve skin texture, radiance, and hydration.

Physician-tested to complement anti-wrinkle neurotoxin injections and effective as a needle-free wrinkle serum on its own, P-TIOX provides 24-hour hydration and supports smoother, more refined-looking skin in as little as 1 week. Ideal for dry, normal, oily, combination, sensitive, aging-looking skin and fine lines. To learn more about Aging Skin & Wrinkles, explore our Anti-Aging Skin Care Products collection.

SkinCeuticals P-TIOX Sizes & Options

  • 30 mL / 1 fl oz

SkinCeuticals P-TIOX Benefits

  • Anti-wrinkle peptide serum for expression lines, fine lines, and visible wrinkles
  • Visibly reduces 9 types of expression lines, including areas neurotoxin injections may not treat
  • Reveals glass skin radiance in as little as 1 week
  • Provides intense 24-hour hydration for smoother, more supple-looking skin
  • Advanced peptide complex helps soften the look of contraction lines
  • 5% PHA supports gentle exfoliation, smoother texture, and visible radiance
  • 5% niacinamide supports the moisture barrier and improves uneven-looking tone
  • 1% laminaria extract helps hydrate and soothe the skin
  • Physician-tested to complement anti-wrinkle neurotoxin injections
  • Fragrance-free, silicone-free, and paraben-free formula for all skin types and tones

Clinical Proof

  • clinically proven to reduce the appearance of 9 types of expression lines
  • In 1 week, visibly improves smoothness, refines the look of pores, and reveals glass skin radiance
  • In 12 weeks, visibly reduces expression lines including nasolabial folds, forehead wrinkles, glabellar wrinkles, crow’s feet, cheek folds, marionette wrinkles, dynamic under-eye wrinkles, inter-ocular lines, and global fine lines
  • Shows 20% reduction in global fine lines
  • Shows 16% improvement in smoothness
  • Shows 10% improvement in radiance

Skin Types

  • Dry
  • Normal
  • Oily
  • Combination
  • Sensitive
  • Aging
  • Fine Lines and Wrinkles

Related skin concerns

Anti-aging/wrinkles

Applicable body parts

Face & Neck

Key ingredients

  • Advanced Peptide Complex (Hexapeptide + Dipeptide) — Helps soften and reduce the appearance of expression/contraction lines.
  • 5% Polyhydroxy Acid (PHA / Gluconolactone) — Gently exfoliates to smooth skin texture and promote a radiant glow.
  • 5% Niacinamide (Vitamin B3) — Strengthens the skin’s moisture barrier, improves discoloration, and supports overall skin tone balance.
  • 1% Laminaria Extract — A seaweed-derived ingredient that soothes, hydrates, and enhances skin radiance.

All ingredients

Aqua / Water / Eau / Niacinamide / Gluconolactone / Butylene Glycol / Peg/Ppg/Polybutylene Glycol-8/5/3 Glycerin / Alcohol Denat. / Pentylene Glycol / Methyl Gluceth-20 / Glycerin / Potassium Hydroxide / Hydroxyethylcellulose / Salicylic Acid / Chlorphenesin / Phytic Acid / Adenosine / Sodium Benzoate / Laminaria Digitata Extract / Dipeptide Diaminobutyroyl Benzylamide Diacetate / Acetyl Hexapeptide-8

  • 1. Cleanse & Prep: Start with clean, dry skin.
  • 2. Apply Serum: Dispense 1–2 pumps of SkinCeuticals P-TIOX into your palm and gently smooth over the forehead, around the eyes (crow’s feet area), between the brows, smile lines, chin, and neck—focusing on areas with visible expression lines.
  • 3. Layer Skincare: Follow with your regular SkinCeuticals moisturizer. If using in the morning, always finish with a broad-spectrum sunscreen SPF 30+ to protect results.
  • 4. Use Daily: Apply twice daily (morning and evening) for best results.
  • 💡 Pro Tip: P-TIOX can be used alone or alongside in-office neurotoxin treatments to enhance and prolong results.
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SkinCeuticals P-TIOX Anti-Wrinkle Peptide Serum

SkinCeuticals P-TIOX Anti-Wrinkle Peptide Serum

Regular price $150
Regular priceSale price $150

Size

30 mL / 1 fl oz

Benefits of SkinCeuticals P-TIOX Anti-Wrinkle Peptide Serum

• Visibly reduces 9 types of expression lines, even those neurotoxin injections do not treat
• Reveals glass skin radiance in 1 week
• Provides intense 24-hour hydration to help maintain smooth, supple skin.
• Physician-tested to complement anti-wrinkle neurotoxin injections
• Suitable for all skin types and tones, even sensitive skin.
• Free from fragrance, silicone, and parabens for a gentler application.

 benefits
Ideal For Skin Types

Ideal For Skin Types

DryNormalOilyCombinationSensitiveAgingFine Lines and Wrinkles
Target Areas

Target Areas

Anti-aging/wrinkles
Application Areas

Application Areas

Face & Neck

Questions?
We have answers.

  1. What is SkinCeuticals P-Tiox used for?
    SkinCeuticals P-Tiox is designed to help smooth the look of fine lines and expression wrinkles while supporting overall skin texture. It works well as a daily treatment to keep skin looking more refined and balanced.
  2. How does SkinCeuticals P-Tiox fit into a skincare routine?
    Apply SkinCeuticals P-Tiox to clean, dry skin before moisturizer and sunscreen. It layers easily with other serums and treatments, making it simple to include in both morning and evening routines.
  3. Who should use SkinCeuticals P-Tiox?
    SkinCeuticals P-Tiox is ideal for anyone noticing early signs of aging, especially fine lines caused by repeated facial movements. It’s suitable for most skin types and works well alongside professional treatments.
  4. Can SkinCeuticals P-Tiox be combined with other SkinCeuticals products?
    Yes, SkinCeuticals P-Tiox pairs well with antioxidant serums, moisturizers, and SPF. Using it consistently with a complete routine can help enhance overall results and support healthier-looking skin.
  5. How long does it take to see results from SkinCeuticals P-Tiox?
    Many users start noticing smoother-looking skin within a few weeks of regular use. With continued application, improvements in the appearance of fine lines and skin texture typically become more visible over time.
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